Therapeutic vaccine candidates using viral vectors encoding LMP2 have productively induced virus-unique CD8⁺ T mobile responses in early-section medical trials. On top of that, adoptive T mobile therapies like posoleucel also concentrate on LMP2 together with other latency proteins like EBNA1, reinforcing its significance like a conserved and immunodominant antigen.
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Peptide Pools can be employed to promote antigen-specific CD4+ and CD8+ T cells. The activated T cells can then be detected, quantified or isolated for Investigation depending on produced cytokines and upregulated activation markers.